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GSK-656 hydrochloride

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SI-5212

GSK-656 hydrochloride, >98% (HPLC)

CAS No. : [2131798-13-3]

Synonyms : GSK-3036656 hydrochloride

IUPAC Name : (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol hydrochloride

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Chemical Properites
Mol. Formula :
C10H13BClNO4 . HCl
Mol. Weight :
293.94
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-656 hydrochloride is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM.

References : Li X. et al.: J. Med Chem., 60(19), 8011-8026, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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