GSK-682753A

SI-7427

GSK-682753A, >98% (HPLC)

CAS No. : [1334294-76-6]

IUPAC Name : (E)-8-(3-(4-Chlorophenyl)acryloyl)-3-(3,4-dichlorobenzyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-682753A selectively targets EBI2 as a potent inverse agonist, inhibiting receptor activity with an IC₅₀ of 53.6 nM. This pharmacological profile supports its use in studies of EBI2‑dependent immune regulation and GPCR‑driven inflammatory responses.

References : Benned-Jensen T. et al.: J. Biol. Chem., 286(33), 29292-302, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.