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GSK-737

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SI-6485

GSK-737, >98% (HPLC)

CAS No. : [2748687-95-6]

IUPAC Name : (S)-N-Cyclopropyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-(1-(pyridin-2-yl)ethoxy)benzamide

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Chemical Properites
Mol. Formula :
C20H21N5O2
Mol. Weight :
363.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-737 inhibits BRD4 BD1 and BD2 with pIC50 values of 5.3 and 7.3 and displays low clearance alongside good solubility and permeability in rat, making it a useful tool for probing BRD4‑dependent transcriptional regulation.

References : Aylott E. H. et al.: J. Med. Chem., 64(6), 3249-3281, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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