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GSK -789

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SI-7059

GSK -789, >98% (HPLC)

CAS No. : [2540591-06-6]

IUPAC Name : (3R,4R)-N-Cyclohexyl-4-((5-(furan-2-yl)-3-methyl-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl)amino)-1-methylpiperidine-3-carboxamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C26H33N5O3
Mol. Weight :
463.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-789 selectively targets BET BD1, inhibiting leukemia‑cell growth and suppressing LPS‑evoked MCP‑1, TNFα, and IL‑6 production in human whole blood. Its antiproliferative, anti‑inflammatory, and immunomodulatory effects make it a valuable tool compound for research in leukemia and other inflammatory or immune‑related disorders.

References : Watson R. J. et al.: J. Med. Chem., 63(17), 9045-9069, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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