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GSK-7975A

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SI-6874

GSK-7975A, >98% (HPLC)

CAS No. : [1253186-56-9]

IUPAC Name : 2,6-Difluoro-N-(1-(4-hydroxy-2-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

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Chemical Properites
Mol. Formula :
C18H12F5N3O2
Mol. Weight :
397.31
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK‑7975A potently inhibits CRAC channel activity and is orally active, making it a valuable tool for probing Ca²⁺‑dependent signaling pathways in immune and inflammatory responses.

References : Ashmole I. et al.: J. Allergy Clin. Immunol., 129(6), 1628-35, e2, 2012; Rice L. V. et al.: Eur. J. Pharmacol., 704(1-3), 49-57, 2013; Wen L. et al. Gastroenterology, 149(2), 481-92, e7, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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