GSK-805

SI-6853

GSK-805, >98% (HPLC)

CAS No. : [1426802-50-7]

IUPAC Name : N-(2,6-Dichloro-2'-(trifluoromethoxy)-[1,1'-biphenyl]-4-yl)-2-(4-(ethylsulfonyl)phenyl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-805 is a potent, selective RORγt inhibitor with oral activity and CNS penetration. It blocks RORγ signaling and Th17 differentiation (pIC₅₀ = 8.4 and >8.2) and suppresses Th17 functional responses, supporting its use in studies of adaptive immunity and Th17‑driven inflammation.

References : Wang Y. et al.: ACS Med. Chem. Lett., 6(7), 787-792, 2015; Xiao S. et al.: Immunity, 40(4), 477-89, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.