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GSK-8175

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SI-3836

GSK-8175, >98% (HPLC)

CAS No. : [1423007-82-2]

Synonyms : GSK-2878175; GSK8175; GSK-175; GSK-175A

IUPAC Name : 6-(N-(7-Chloro-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)methylsulfonamido)-5-cyclopropyl-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide

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Chemical Properites
Mol. Formula :
C27H23BClFN2O6S
Mol. Weight :
568.81
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-8175 is a potent, pan-genotypic, second generation HCV NS5B palm polymerase inhibitor with EC50 of 0.4-9.7 nM.

References : Chong Y. P. et al.: J. Med. Chem., 62(7), 3254-3267, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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