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GSK-843

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SI-5208

GSK-843, >98% (HPLC)

CAS No. : [1601496-05-2]

MDL No. : MFCD30536593

IUPAC Name : 3-(Benzo[d]thiazol-5-yl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)thieno[3,2-c]pyridin-4-amine

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Chemical Properites
Mol. Formula :
C19H15N5S2
Mol. Weight :
377.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM.

References : Mandal P. et al.: Mol Cell., 56(4), 481-495, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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