Gunagratinib

SI-7548

Gunagratinib, >98% (HPLC)

CAS No. : [2211082-53-8]

Synonyms : ICP-192

IUPAC Name : (S)-1-(1-Acryloylpyrrolidin-3-yl)-3-((3,5-dimethoxyphenyl)ethynyl)-5-(methylamino)-1H-pyrazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Gunagratinib irreversibly inhibits FGFR1–4 via covalent engagement, offering potent, selective, and orally active suppression of FGFR signaling with low toxicity. Its alkyne functionality enables CuAAC click‑chemistry conjugation, making it useful both as an FGFR‑targeted tool compound and as a chemical probe in cancer research.

References : Ye G. et al.: Journal of Clinical Oncology 39, 4092-4092, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.