Gusacitinib hydrochloride

SI-6326

Gusacitinib hydrochloride, >98% (HPLC)

CAS No. : [2228989-14-6]

Synonyms : ASN-002 hydrochloride

IUPAC Name : 2-(1-(4-((4-(4-Hydroxypiperidin-1-yl)phenyl)amino)-5-oxo-5,6-dihydropyrimido[4,5-d]pyridazin-2-yl)piperidin-4-yl)acetonitrile;hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Gusacitinib hydrochloride is a potent dual SYK/JAK inhibitor with low‑nanomolar activity across SYK and JAK1/2/3/TYK2. It effectively suppresses inflammatory signaling relevant to atopic dermatitis and is used in research on chronic hand eczema and cancers such as basal cell carcinoma.

References : Xie Z. et al.:J. Med. Chem., 64(3), 1283-1345, 2021; Garcia-Melendo C. et al.: Actas. Dermo-Sifiliográficas, 112(6), 503-515, 2021; Reddy S. et al.: Cancer Res., 75 (15), 792, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.