GW-610742

SI-6616

GW-610742, >98% (HPLC)

CAS No. : [317318-84-6]

Synonyms : GW-0742

IUPAC Name : 2-(4-(((2-(3-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methyl)thio)-2-methylphenoxy)acetic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GW-610742 potently activates PPARβ/δ, with an IC₅₀ of 1 nM for human PPARδ and EC₅₀ values of 1 nM, 1.1 µM, and 2 µM for PPARδ, PPARα, and PPARγ, respectively. Its pronounced selectivity makes it a valuable tool for probing PPARδ‑regulated metabolic pathways.

References : Sznaidman M. L. et al.: Bioorg. Med. Chem. Lett., 13(9), 1517-21, 2003; Smith S. A. et al.: J. Neurosci. Res., 77(2), 240-9, 2004; Galuppo M. et al.: Int. J. Immunopathol Pharmacol., 23(4), 1033-46, 2010; Kuo S. C. et al.: Horm Metab. Res., 45(12), 880-6, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.