H3B-6527

SI-7067

H3B-6527, >98% (HPLC)

CAS No. : [1702259-66-2]

IUPAC Name : N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4-ethylpiperazin-1-yl)phenyl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : H3B‑6527 is an orally active and highly selective covalent FGFR4 inhibitor with sub‑nanomolar potency. It maintains > 250‑fold selectivity relative to FGFR1–3 and demonstrates strong anti‑cancer efficacy in preclinical studies.

References : Joshi J. J. et al.: Cancer Res. 77(24), 6999-7013, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.