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hBChE-IN-2

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SI-7929

hBChE-IN-2, >98% (HPLC)

CAS No. : [2923366-36-1]

IUPAC Name : 4-((5-(Diethylcarbamoyl)-1-isopentyl-1H-benzo[d]imidazol-2-yl)methyl)phenyl dimethylcarbamate

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Chemical Properites
Mol. Formula :
C27H36N4O3
Mol. Weight :
464.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a dual‑acting small molecule that functions as a butyrylcholinesterase (BChE) inhibitor (IC50= 0.62 µM) and a CB2 receptor agonist. Through this combined mechanism, hBChE‑IN‑2 exhibits neuroprotective activity, making it a useful tool compound for studying cholinergic regulation, CB2‑mediated signaling, and neurodegeneration models.

References : Spatz P. et al.: J. Med. Chem., 66(9), 6414-6435, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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