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HBV-IN-25

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SI-7136

HBV-IN-25, >98% (HPLC)

CAS No. : [2161364-69-6]

IUPAC Name : (R)-1-(5-Chloro-9-oxo-9H-xanthen-3-yl)pyrrolidine-3-carboxylic acid

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C18H14ClNO4
Mol. Weight :
343.76
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an orally active, potent HBV cccDNA reducer with strong antiviral activity. It shows anti‑HBeAg potency (IC50 = 0.58 μM) and anti‑HBV activity (IC50 = 1.15 μM), along with excellent aqueous solubility (LYSA > 452 μg/mL) and favorable PK properties. It demonstrates no cellular toxicity, making it a valuable tool compound for HBV replication and cccDNA‑targeted research.

References : Chen D. et al.: J. Med. Chem., 65(16), 10938-10955, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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