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CAS No. : [2814571-89-4]
IUPAC Name : (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C28H28FN5O2 | Mol. Weight : 485.56 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is a pyridazinone‑derived benzamide HDAC inhibitor with potent class I HDAC activity, strong SKM‑1 antiproliferative effects, and clear G1 arrest/apoptosis induction. It shows excellent in vivo efficacy in SKM‑1 xenografts, better performance in immunocompetent mice, favorable PK, low hERG liability, and minimal interspecies metabolic variation, making it a promising HDAC inhibitor candidate for further development.
References : Li D. et al.: s: J. Med. Chem., 66(10), 7016-7037, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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