HG-10-102-01

SI-8017

HG-10-102-01, >98% (HPLC)

CAS No. : [1351758-81-0]

IUPAC Name : (4-((5-Chloro-4-(methylamino)pyrimidin-2-yl)amino)-3-methoxyphenyl)(morpholino)methanone

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : HG‑10‑102‑01 is a brain‑penetrant LRRK2 inhibitor with nanomolar potency against both WT and G2019S variants. It also targets MNK2 and MLK1 at micromolar concentrations. These properties support its use in probing LRRK2‑dependent signaling pathways relevant to Parkinson’s disease.

References : Choi H. G. et al.: ACS. Med. Chem. Lett., 3(8), 658-662, 2012; Wang M. et al.: Bioorg. Med. Chem. Lett., 27(6), 1351-1355, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.