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HIV-1 inhibitor-56

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SI-7930

HIV-1 inhibitor-56, >98% (HPLC)

CAS No. : [2952530-45-7]

IUPAC Name : (E)-4-((5-Amino-1-((5-(2-cyanovinyl)naphthalen-1-yl)sulfonyl)-1H-1,2,4-triazol-3-yl)amino)-2-chlorobenzonitrile

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C22H14ClN7O2S
Mol. Weight :
475.91
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a potent non‑nucleoside reverse transcriptase inhibitor exhibiting sub‑nanomolar antiviral activity (EC50 = 0.24 nM) against wild‑type HIV‑1 in TZM cells. Its ability to cross the blood–brain barrier highlights its utility for investigating CNS‑penetrant HIV therapeutics.

References : Lane T. et al.: J. Med. Chem., 66(9), 6193-6217, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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