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Homocapsaicin-I-d3

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Homocapsaicin-I-d3, >98% (CP)

Isotopic Purity : 99 atom % D

Related CAS No. : [58493-48-4] of the unlabelled compound

Synonyms : E-Homocapsaicin-d3; Homocapsaicin-d3

IUPAC Name : (E)-N-(4-Hydroxy-3-methoxy-d3 benzyl)-9-methyldec-7-enamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C19H26D3NO3
Mol. Weight :
322.46
Appearance :
Oily liquid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Homocapsaicin-I and an analog of Capsaicin, which is the principal pungent component in hot peppers, including red chilli peppers, and it has a profound antiproliferative effect on prostate cancer cells, inducing the apoptosis of both androgen receptor (AR)-positive (LNCaP) and -negative (PC-3, DU-145) prostate cancer cell lines associated with an increase of p53, p21, and Bax.Capsaicin inhibited NF-kappa activation by preventing its nuclear migration. This can be used as an internal reference standard.

References : Kozukue N. et al.: J. Agric. Food Chem. 53, 9172, 2005; Choi S. et al.: J. Agric. Food Chem. 54, 9224, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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