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HPOB

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SL-1648

HPOB, >98%

CAS No. : [1429651-50-2]

MDL No. : MFCD27952937

IUPAC Name : 4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenyl-benzeneacetamide

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Chemical Properites
Mol. Formula :
C17H18N2O4
Mol. Weight :
314.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : HPOB is a highly potent and selective inhibitor of histone deacetylase 6 (HDAC6) with IC50 of 56 nM, >30 fold less potent against other HDACs.

References : Lee J. H. et al.: Proc Natl Acad Sci U S A. 110(39),15704, 2013; Li Z. Y. et al.: Neurochem Int., 99, 239,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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