HST-1011

SI-7541

HST-1011, >98% (HPLC)

IUPAC Name : 6-((5-Azaspiro[2.4]heptan-5-yl)methyl)-2-(3-(3-((4-methyl-4H-1,2,4-triazol-3-yl)methyl)oxetan-3-yl)phenyl)-8-(trifluoromethyl)imidazo[1,5-a]pyridin-3(2H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : HST‑1011 is a potent and selective small‑molecule inhibitor of Cbl‑b, a RING‑type E3 ubiquitin ligase that negatively regulates T‑cell activation. By blocking Cbl‑b’s ligase activity, HST‑1011 enhances T‑cell signaling and effector function, positioning it as a promising immuno‑oncology agent aimed at boosting antitumor immune responses.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.