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Hydrolyzed pomalidomide M11

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Hydrolyzed pomalidomide M11, >98%

CAS No. : [2635-64-5]

Synonyms : Pomalidomide hydrolysis impurity 2; Pomalidomide impurity 3; Pomalidomide impurity J

IUPAC Name : 5-Amino-2-(4-amino-1,3-dioxoisoindolin-2-yl)-5-oxopentanoic acid

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Chemical Properites
Mol. Formula :
C13H13N3O5
Mol. Weight :
291.26
Appearance :
Solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Pomalidomide and related analogs, also an hydrolyzed impurity of Pomalidomide M11. A derivative of Thalidomide. It is anti-angiogenic and also acts as an immunomodulator.

References : Ding X. H. et al.: Bioorg. Med. Chem. 23(9), 1895-1922, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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