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Hydroxy benzo thiophene

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Hydroxy benzo thiophene, >98%

CAS No. : [51868-95-2]

Synonyms : 2-(1-Hydroxyethyl)benzothiophene; Zileuton impurity 1

IUPAC Name : 1-(Benzo[b]thiophen-2-yl)ethan-1-ol

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
250MG395.00
In Stock  Estimated to ship on 20 September 2026
1G1095.00
In Stock  Estimated to ship on 20 September 2026
5G3295.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C10H10OS
Mol. Weight :
178.25
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Zileuton, which is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation. It is used to decrease the symptoms of asthma. Zileuton induces apoptosis while inhibits ferroptosis.

References : Rossi A. et al.: Br. J. Pharmacol., 161(3), 555-570, 2010; Bertran X. et al.: Gut., 38(6), 899-904, 1996; Genovese T. et al.: Br. J. Pharmacol., 153(3), 568-582, 2008; Patel N. S. et al.: Mol Pharmacol., 66(2), 220-227, 2004; Rao N. L. et al.: J. Pharmacol Exp Ther., 321(3), 1154-1160, 2007; Yang Liu et al.: Biol Pharm Bull., 38(8), 1234-9, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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