Hydroxy bosentan-d6

SL-2590

Hydroxy bosentan-d₆, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1246817-57-1]

MDL No. : MFCD19705154

IUPAC Name : 4-(1-Hydroxy-2-methylpropan-2-yl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide-d₆

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Hydroxy bosentan-d₆ is a deuterium labelled version an active metabolite of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ET_A and ET_B receptors.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9(5), 331-350, 2009; Akamata K. et al.: Arthritis Res Ther. 16(2), R86, 2014; Iglarz M. et al.: Life Sci. 118(2), 333-339, 2014; Son G. Y. et al.: PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.