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Hydroxymethyl ivacaftor

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Hydroxymethyl ivacaftor, >98%

CAS No. : [1246213-23-9]

Synonyms : Ivacaftor hydroxymethyl impurity; Ivacaftor impurity 2; Hydroxymethyl ivacaftor M1

IUPAC Name : N-(2-(tert-Butyl)-5-hydroxy-4-(1-hydroxy-2-methylpropan-2-yl)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H28N2O4
Mol. Weight :
408.5
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ivacaftor, which is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.

References : Van Goor F. et al.: Proc Natl Acad Sci U S A. 106(44), 18825-18830, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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