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Hydroxyprogesterone acetate (impurity H)

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Hydroxyprogesterone acetate (impurity H), >98%

Synonyms : 17-(Acetyloxy)pregn-4-ene-3,20-dione; 17-Hydroxypregn-4-ene-3,20-dione acetate; 17-(Acetyloxy)progesterone; 17-Acetoxypregn-4-ene-3,20-dione; 17-Hydroxy progesteroneacetate; 17α-Acetoxypregn-4-ene-3,20-dione; Hydroxyprogesterone acetate; USP Melengestrol acetate related compounds A; Megestrol acetate EP impurity K; Medroxy progesterone EP impurity H; NSC 12191; U 5533

IUPAC Name : (8R,9S,10R,13S,14S,17R)-17-Acetyl-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
10MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C23H32O4
Mol. Weight :
372.51
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Medroxyprogesterone, which is a synthetic form of human progesterone that acts as an agonist at progesterone receptors and can be taken orally. It promotes cell proliferation via the PI3K/Akt signaling pathway and has been shown to inhibit atherosclerosis in mice. However, its progesterone agonist activity is less potent compared to medroxyprogesterone acetate.

References : Saitoh M. et al.: Endocrinology, 146(11), 4917-25, 2005; Ito F. et al.: J. Clin Endocrinol Metab., 99(6), 2188-97, 2014; Freudenberger T. et al.: Br. J. Pharmacol., 158(8), 1951-60, 2009; Yusop S. N. W. et al.: Steroids, 164:108735, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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