I-299

SI-7149

I-299, >98% (HPLC)

CAS No. : [1801903-15-0]

Synonyms : Vps34-IN-5

IUPAC Name : N-(6-Chloro-4-methyl-2'-((2-methylpyrimidin-4-yl)amino)-[3,4'-bipyridin]-5-yl)-2,4-difluorobenzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is an orally active VPS34 kinase inhibitor that achieves 98% target inhibition and exhibits a B‑category IC₅₀, indicating strong potency. It shows additive or synergistic anti‑proliferative activity when combined with EGFR inhibitors in cancer cells. In mouse xenograft models, it is effective when administered orally, either alone or together with erlotinib, supporting its use in non‑small cell lung cancer (NSCLC) research.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.