I-BET-282

SI-6752

I-BET-282, >98% (HPLC)

CAS No. : [1422554-34-4]

IUPAC Name : (R)-4-(8-Methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : I‑BET-282 is a potent, selective pan‑BET inhibitor that targets all eight bromodomains of BRD2, BRD3, and BRD4 while maintaining selectivity over non‑BET bromodomain proteins. It displays pIC₅₀ values ranging from 6.4 to 7.7 for BRD2, BRD3, and BRD4 BD1/BD2 domains.

References : Katherine L. Jones et al.: J. Med. Chem., 64(16), 12200-12227, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.