I-BET-282E

SI-6753

I-BET-282E, >98% (HPLC)

CAS No. : [2885162-99-0]

IUPAC Name : (R)-4-(8-Methoxy-1-(1-methoxypropan-2-yl)-2-(tetrahydro-2H-pyran-4-yl)-1H-imidazo[4,5-c]quinolin-7-yl)-3,5-dimethylisoxazole methanesulfonate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : I‑BET-282E potently inhibits all BET family bromodomains with clear selectivity relative to other bromodomain‑containing proteins. Its activity spans BRD2, BRD3, and BRD4 BD1/BD2 domains, with pIC₅₀ values between 6.4 and 7.7, making it a valuable tool for probing BET‑regulated gene expression.

References : Katherine L. Jones et al.: J. Med. Chem., 64(16), 12200-12227, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.