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Iadademstat dihydrochloride

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SI-6686

Iadademstat dihydrochloride, >98% (HPLC)

CAS No. : [1431303-72-8]

Synonyms : ORY-1001 dihydrochloride; RG-6016 dihydrochloride; RO- 7051790 dihydrochloride

IUPAC Name : (1r,4S)-N1-((1S,2R)-2-Phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride

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Chemical Properites
Mol. Formula :
C15H22N2 • 2HCl
Mol. Weight :
303.27
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Iadademstat dihydrochloride irreversibly inhibits the epigenetic regulator KDM1A/LSD1 with high selectivity, enabling targeted suppression of LSD1‑driven transcriptional pathways relevant to leukemia and other cancers.

References : Maes T. et al.: Epigenomics., 7(4), 609-26, 2015; Tamara Maes et al.: Cancer Cell., 33(3), 495-511.e12, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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