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Ibiglustat hydrochloride

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SI-6986

Ibiglustat hydrochloride, >98% (HPLC)

CAS No. : [1629063-79-1]

Synonyms : Venglustat hydrochloride; SAR-402671 hydrochloride; GZ-402671 hydrochloride

IUPAC Name : (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate hydrochloride

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C20H24FN3O2S • HCl
Mol. Weight :
425.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ibiglustat hydrochloride functions as a potent, orally active, and brain‑penetrant GCS inhibitor. Its pharmacological profile supports its use across multiple glycosphingolipid‑related disorders, including Gaucher disease type 3, GBA‑linked Parkinson’s disease, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.

References : Viel C. et al.: Sci. Rep., 11(1), 20945, 2021; Peterschmitt M. J. et al.: Clin. Pharmacol. Drug Dev., 10(1), 86-98, 2021; Stojkovska I. et al.: Cell Tissue Res., 373(1), 51-60, doi:10.1007/s00441-017-2704-y, 2018; Itier J. M. et al.: J. Inherit Metab. Dis., 37(6), 1013-22, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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