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CAS No. : [1629063-80-4]
Synonyms : Venglustat succinate; SAR-402671 succinate; GZ-402671 succinate
IUPAC Name : (S)-Quinuclidin-3-yl (2-(2-(4-fluorophenyl)thiazol-4-yl)propan-2-yl)carbamate succinate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H24FN3O2S • C4H6O4 | Mol. Weight : 507.58 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Ibiglustat succinate, the succinate salt of Venglustat, functions as a potent, orally active, and brain‑penetrant GCS inhibitor. Its pharmacological profile supports its use across multiple glycosphingolipid‑related disorders, including Gaucher disease type 3, GBA‑linked Parkinson’s disease, Fabry disease, GM2 gangliosidosis, and autosomal dominant polycystic kidney disease.
References : Viel C. et al.: Sci. Rep., 11(1), 20945, 2021; Peterschmitt M. J. et al.: Clin. Pharmacol. Drug Dev., 10(1), 86-98, 2021; Iva Stojkovska. et al.: Cell Tissue Res., 2017; Itier J. M. et al.: J. Inherit. Metab. Dis., 37(6), 1013-1022, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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