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Ibrutinib dimer impurity 3

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Ibrutinib dimer impurity 3, >98%

IUPAC Name : (R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C42H37N11O3
Mol. Weight :
743.83
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ibrutinib, which is a selective, irreversible BTK inhibitor. Ibrutinib is used to treat adults with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL).

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107(29), 13075-13080, 2010; Herman S. E. et al.: Blood. 117(23), 6287-6296, 2011; Chang B. Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7(1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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