Idasanutlin

SI-6494

Idasanutlin, >98% (HPLC)

CAS No. : [1229705-06-9]

Synonyms : RG-7388

IUPAC Name : 4-((2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Idasanutlin selectively disrupts the p53–MDM2 interaction with nanomolar potency (IC₅₀ = 6 nM), enabling reactivation of p53‑dependent cell‑cycle arrest and apoptosis in MDM2‑driven cancer models.

References : Ding Q. et al.: J. Med. Chem., 56(14), 5979-83, 2013; Higgins B. et al.: Clin Cancer Res., 20(14), 3742-3752, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.