IDO1/2-IN-1

SI-6889

IDO1/2-IN-1, >98% (HPLC)

CAS No. : [2310286-45-2]

IUPAC Name : (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(4-((2-hydroxyethoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This potently inhibits both IDO1 and IDO2 (IC₅₀ = 28 nM and 144 nM), representing the first dual‑targeting agent in this class. It shows antitumor efficacy in preclinical models and is orally active, making it a valuable tool for probing IDO‑mediated immunometabolic pathways.

References : He X. et al.: J. Med. Chem., 64(24), 17950-17968, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.