IDO1/2-IN-1 hydrochloride

SI-6890

IDO1/2-IN-1 hydrochloride, >98% (HPLC)

CAS No. : [2310286-60-1]

IUPAC Name : (Z)-N-(3-Bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(4-((2-hydroxyethoxy)methyl)-1H-1,2,3-triazol-1-yl)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This potently inhibits both IDO1 and IDO2 (IC₅₀ = 28 nM and 144 nM), representing the first dual‑targeting agent in this class. It displays antitumor efficacy in preclinical models and is orally active, supporting its use in research on IDO‑mediated immune suppression and cancer progression.

References : He X. et al.: J. Med. Chem., 64(24), 17950-17968, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.