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CAS No. : [2328099-11-0]
IUPAC Name : N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C25H22F4N2O3 | Mol. Weight : 474.46 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : IDO1‑IN‑19 is an orally active IDO1 inhibitor that also shows weak CYP2C9 inhibition (IC50 = 8.64 µM). In addition, it exhibits functional activity on cardiac ion channels, with IC50 values of 12 µM for IKr, 40 µM for INa, and 8.3 µM for ICa. Despite these off‑target effects, the compound retains potential utility as a tool molecule for studying IDO1‑related cancer biology.
References : Li. D. et al.: J. Med. Chem., 65(8), 6001-6016, 2022.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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