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IDO5L

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SI-7876

IDO5L, >98% (HPLC)

CAS No. : [914471-09-3]

IUPAC Name : (E)-4-Amino-N-(3-chloro-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide

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Chemical Properites
Mol. Formula :
C9H7ClFN5O2
Mol. Weight :
271.64
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : IDO5L inhibits IDO with low‑nanomolar potency (IC50 = 67 nM), making it suitable for studies of tryptophan catabolism, immune suppression, and tumor‑associated metabolic signaling.

References : Yue E. W. et al.: J. Med.Chem., 52(23), 7364-7, 2007; Huang X. et al.: J. Labelled Comp Radiopharm., 58(4), 156-62, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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