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IDX-184

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SI-4153

IDX-184, >98% (HPLC)

CAS No. : [1036915-08-8]

MDL No. : MFCD23381633

Synonyms : IDX184

IUPAC Name : S-(2-(((((2R,3R,4R,5R)-5-(2-Amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(benzylamino)phosphoryl)oxy)ethyl) 3-hydroxy-2,2-dimethylpropanethioate

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Chemical Properites
Mol. Formula :
C25H35N6O9PS
Mol. Weight :
626.62
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : IDX-184 is a nucleotide prodrug designed to enhance formation in the liver of the active triphosphate of 2′-methylguanosine (2′-MeG), a potent and specific polymerase inhibitor of the hepatitis C virus (HCV)

References : Zhou L. et al.: J. Med. Chem., 58(8), 3445-3458, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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