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Ilorasertib

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SI-4893

Ilorasertib, >98% (HPLC)

CAS No. : [1227939-82-3]

MDL No. : MFCD25976780

Synonyms : ABT-348

IUPAC Name : 1-(4-(4-Amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno[3,2-c]pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea

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Chemical Properites
Mol. Formula :
C25H21FN6O2S
Mol. Weight :
488.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ilorasertib is a novel, potent and orally bioavailable inhibitor of the aurora kinases as well as the VEGF and PDGF families of receptor tyrosine kinases.

References : Gao C. et al.: J. Mol. Model., 21(7), 167,2015; Glaser K. B. et al.: J. Pharmacol Exp Ther., 343(3), 617-627, 2012; Curtin M. L. et al.: Bioorg Med Chem Lett., 22(9), 3208-3212, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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