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Imlunestrant

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SI-8090

Imlunestrant, >98% (HPLC)

CAS No. : [2408840-26-4]

Synonyms : LY-3484356

IUPAC Name : (R)-5-(4-(2-(3-(Fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-8-(trifluoromethyl)-5H-chromeno[4,3-c]quinolin-2-ol

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Chemical Properites
Mol. Formula :
C29H24F4N2O3
Mol. Weight :
524.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Imlunestrant is an orally active SERD with strong potency and selectivity, acting as a pure ER antagonist. It provides sustained inhibition of ER‑driven transcriptional programs and cell growth, supporting its use in ER⁺ aBC and EEC research.

References : Komal L. Jhaveri et al.: J. Clin. Oncol., 39(15), 1050, 2021; Hernando C. et al.: Int. J. Mol. Sci., 22(15), 7812, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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