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IMP-1710

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SI-8138

IMP-1710, >98% (HPLC)

CAS No. : [2383117-96-0]

IUPAC Name : (R)-2-(4-(5-Ethynyl-1H-pyrrolo[2,3-b]pyridin-3-yl)indoline-1-carbonyl)pyrrolidine-1-carbonitrile

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Chemical Properites
Mol. Formula :
C23H19N5O
Mol. Weight :
381.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : IMP‑1710 selectively inhibits UCHL1 with low‑nanomolar potency (IC50 = 38 nM) and acts as a robust probe for profiling UCHL1 targets in living cells. Its alkyne handle allows CuAAC‑based conjugation with azide‑bearing molecules. IMP‑1710 also exhibits antifibrotic effects, making it valuable for idiopathic pulmonary fibrosis research.

References : Panyain N. et al.: J. Am. Chem. Soc., 142(28), 12020-12026, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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