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INCB-059872

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SI-6200

INCB-059872, >98% (HPLC)

CAS No. : [1802909-49-4]

IUPAC Name : 1-((4-(Methoxymethyl)-4-((((1R,2S)-2-phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)cyclobutane-1-carboxylic acid

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Chemical Properites
Mol. Formula :
C23H34N2O3
Mol. Weight :
386.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : INCB-059872 is an orally active, irreversible LSD1 inhibitor that forms covalent adducts with FAD to achieve durable enzymatic blockade. It induces myeloid differentiation markers (CD86, CD11b), inhibits proliferation, and serves as a key tool compound for myeloid leukemia research.

References : Johnston G. et al.: Gene, 752, 144758, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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