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Indirubin derivative E-804

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SI-7771

Indirubin derivative E-804, >98% (HPLC)

CAS No. : [854171-35-0]

IUPAC Name : (2Z,3Z)-3-((3,4-Dihydroxybutoxy)imino)-[2,3'-biindolinylidene]-2'-one

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Chemical Properites
Mol. Formula :
C20H19N3O4
Mol. Weight :
365.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Indirubin derivative E-804 selectively targets IGF1R with an IC50 of 0.65 µM. As a structurally optimized indirubin analogue, it is employed to investigate IGF1R‑dependent growth and survival signaling.

References : Cheng X. et al.: J. Med. Chem., 60(12), 4949-4962, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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