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INE-963

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SI-6964

INE-963, >98% (HPLC)

CAS No. : [2640567-43-5]

IUPAC Name : 4-(Aminomethyl)-1-(5-(6-isopropyl-2-methoxypyridin-3-yl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl)piperidin-4-ol

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Chemical Properites
Mol. Formula :
C19H26N6O2S
Mol. Weight :
402.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : INE-963 demonstrates potent nanomolar activity (EC50 = 3–6 nM) against blood‑stage malaria parasites and acts rapidly to clear parasitemia. These properties position it as a promising candidate for single‑dose treatment of uncomplicated malaria.

References : Taft B. R. et al.: J. Med. Chem., 65(5), 3798-3813, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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