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Infigratinib-Boc

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SI-6726

Infigratinib-Boc, >98% (HPLC)

CAS No. : [2504949-83-9]

IUPAC Name : tert-Butyl 4-(4-((6-(3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)phenyl)piperazine-1-carboxylate

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Chemical Properites
Mol. Formula :
C29H35Cl2N7O5
Mol. Weight :
632.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Infigratinib‑Boc is a Boc‑protected form of the ATP‑competitive pan‑FGFR inhibitor Infigratinib. This protected intermediate is commonly used in synthetic routes toward Infigratinib analog and labelled derivatives.

References : Guangyan Du et al.: Angew. Chem. Int. Ed. Engl., 60(29), 15905-15911, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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