Infigratinib-d3

SI-6723

Infigratinib-d₃, >98% (HPLC)

Synonyms : BGJ-398-d₃; NVP-BGJ-398-d₃

IUPAC Name : 3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-(methyl-d₃)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Infigratinib‑d₃ is a deuterium‑labelled version of Infigratinib. This can be used as an internal standard or for isotope‑based analytical investigations. Infigratinib potently inhibits FGFR1–3 at low‑nanomolar concentrations and shows weaker activity against FGFR4. It is useful for mechanistic and pharmacokinetic studies involving FGFR‑targeted signaling.

References : Guagnano V. et al.: J. Med. Chem., 54(20), 7066-83, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.