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IOX2

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SL-1030

IOX2, >98%

CAS No. : [931398-72-0]

MDL No. : MFCD22580424

IUPAC Name : N-​[[1,​2-​Dihydro-​4-​hydroxy-​2-​oxo-​1-​(phenylmethyl)-​3-​quinolinyl]carbonyl]-​glycine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG95.00
Back Order  Estimated to ship on 29 November 2026
10MG115.00
Back Order  Estimated to ship on 29 November 2026
25MG245.00
Back Order  Estimated to ship on 29 November 2026
50MG445.00
Back Order  Estimated to ship on 29 November 2026
100MG595.00
Back Order  Estimated to ship on 29 November 2026
We accept
Chemical Properites
Mol. Formula :
C19H16N2O5
Mol. Weight :
352.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : IOX2 is a selective inhibitor of the hypoxia inducible factor (HIF) prolyl-hydroxylases, which is a master regulator of the cellular-response to hypoxia, are regulated by the post-translational modification of prolyl-residues in oxygen-dependent degradation domains in the HIFα subunit. HIFα prolyl-hydroxylation signals for its degradation by the proteosome.

References : Murray J. K. et al.: J. Comb. Chem., 12, 676, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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