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IOX2-d5

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SL-1031

IOX2-d5, >98% (CP)

Isotopic Purity : 98 atom % D

MDL No. : MFCD30146009

Related CAS No. : [931398-72-0] of the unlabelled compound

IUPAC Name : (4-Hydroxy-2-oxo-1-((phenyl-d5)methyl)-1,2-dihydroquinoline-3-carbonyl)glycine

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Chemical Properites
Mol. Formula :
C19H11D5N2O5
Mol. Weight :
357.37
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : IOX2 is a selective and potent inhibitor of prolyl hydroxylases (PHD). Stabilization of HIF-1R through inhibition of PHD has been examined as a potential treatment for ischemic diseases including anemia, myocardial infarction, and stroke. This can be used as an internal reference standard for metabolic studies.

References : Tian Y. et al.: J. Biol. Chem., 286(15), 13041, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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