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Ipatasertib dihydrochloride

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SI-5282

Ipatasertib dihydrochloride, >98% (HPLC)

CAS No. : [1396257-94-5]

MDL No. : MFCD28963954

Synonyms : GDC-0068 dihydrochloride; RG-7440 dihydrochloride

IUPAC Name : (S)-2-(4-Chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one dihydrochloride

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H32ClN5O2 . 2HCl
Mol. Weight :
530.92
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ipatasertib dihydrochloride is a highly selective and ATP-competitive pan-AKT inhibitor. It is currently in phase II trials for treatment of breast cancer.

References : Blake J. F. et al.: J. Med Chem., 55(18), 8110-27, 2012; Lin J. et al.: Clin Cancer Res., 19(7), 1760-72, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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