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Irinotecan hydrochloride

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SI-6470

Irinotecan hydrochloride, >98% (HPLC)

CAS No. : [100286-90-6]

Synonyms : (+)-Irinotecan hydrochloride; CPT-11 hydrochloride; VAL-413

IUPAC Name : (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate hydrochloride

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C33H38ClN4O6 • HCl
Mol. Weight :
623.15
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Irinotecan hydrochloride is the hydrochloride salt of Irinotecan, a topoisomerase I inhibitor that blocks DNA strand religation by trapping the topo I–DNA complex. It is primarily employed in the treatment of colon and rectal cancers.

References : Morales C. et al.: J. Neurooncol., 56(3), 219-26, 2002; Pavillard V. et al.: Cancer Chemother. Pharmacol., 49(4), 329-35, 2022; Allegrini G. et al.: Cancer Chemother. Pharmacol., 53(3), 261-6, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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